Endocrine Abstracts

Introduction: One of the objectives of weight loss in obesity is to prevent metabolic disorders. An important component in the maintenance of the achieved results is a change of eating behavior.Goal: To study the effect of liraglutide 3.0 mg on the dynamics of metabolic parameters and eating behavior in patients with obesity.Materials and methods: The study enrolled 42 obese patients in whom anthropometric parameters, metabolic par...

Introduction: Liraglutide 3.0 mg could be effective option for obesity management. It is known that patients who have ≥5% weight loss in 16 weeks (‘early responders’ (ERs)) will have ≥10% weight loss in 56 weeks [1]. Predictors of this early response (ER) in 16 weeks are unknown.Methods: 22 obese patients (30% men; median age 40.0 [33.0; 48.5]) were recruited. The exclusion criteria were diabetes, psychotic disorders, obesity due ...

Introduction: Obesity is one of the most common endocrine disorders. Obesity can either be a symptom of numerous diseases or be associated with them, including cases, when patient does not have other complaints besides excess weight. This should be considered before initiating obesity treatment.Case: A 42-year-old male visited endocrinologist, complaining of overweight. Minimum weight from his adulthood was 70 kg, maximum was for that moment–124.5 k...

IntroductionTelemedicine is a useful tool for improving the availability of medical care, especially in the era of COVID-19. It is required to study the needs of the Russian population for telemedicine services for each specific disease.MethodsIn Russian Federation telemedicine consultations (TMC) have been legally allowed since 2018. According to the law, if the patient has not previously attended a face-to-...

Rationale: The COVID-19 pandemic has accelerated the development of telemedicine technologies. Today there is evidence of the successful use of telemedicine in various areas of healthcare, particularly in endocrinology. At the same time, there is not enough information for efficient integration of telemedicine into the routine management of patients.Aim: The aim of this work was a clinical and demographic analysis of “doctor-patient” telemedici...

Introduction: Results obtained from PRIMAVERA study have demonstrated that 7.5% of obese individuals does not respond to sibutramine therapy. The aim of the study was to evaluate if GNB3, SERT, NET, TPH2 genes polymorphisms are associated with the results of obesity treatment with sibutramine.Methods: 69810 obese patients took sibutramine for at least 3 months. According to the results of 3 months therapy, we formed two groups of patients: 1) &#...

Introduction: Patient’s nutrition is generally considered to be the main cause of the accumulation of excess body weight. However, this accumulation can be mitigated by treatment involving drugs with a central mechanism of action. By using functional Magnetic Resonance Imaging (fMRI) we can meliorate our understanding of the organization of neuronal networks responsible for eating behavior, and see how they respond to the mechanisms of action of sibutramine in the treatm...